Gender-bending fish downstream of WWTPs
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Gender-bending fish downstream of WWTPs 09 Jan 2014 23:56 #6940

  • KeithBell
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Most focus by far in this area of research is about endocrine disrupting chemicals.

But the real problem may be natural estrogens excreted from everyone's intestines. All steroid hormones are derived from cholesterol and its metabolite, coprostanol. Coprostanol is already used as indicator of fecal pollution where testing can distinguish human from livestock waste.

There are no studies about fecal sterols in treated drinking water. This is admitted by the US EPA.
savethewater.org/old13k1fr/2012/09/30/co...scc-2013-keith-bell/

www.colorado.edu/news/releases/2010/06/2...ated-treatment-plant

Over 70% of smallmouth bass are intersex in parts of the Mississippi River and extremely high rates throughout the country per United States Geological Survey (USGS).
www.sciencedaily.com/releases/2009/09/090914172648.htm

Fish feminization is one thing, but my hometown of Chicago sends sewage down the mighty Mississippi River into the Gulf of Mexico feeding algae blooms, creating a massive, toxic, low oxygen Dead Zone where female fish develop testes:
news.nationalgeographic.com/news/2011/05...shwater-environment/

Meanwhile, there is a human global infertility epidemic, both male and female.
articles.latimes.com/2012/aug/15/world/l...srael-sperm-20120816
www.bbc.co.uk/news/health-20593467
www.huffingtonpost.com/2013/11/07/china-...count_n_4233231.html
www.chinadaily.com.cn/china/2012-12/19/content_16030598.htm
www.theatlantic.com/china/archive/2013/0...ise-in-china/279493/
www.ncbi.nlm.nih.gov/pubmed/23327901
www.ncbi.nlm.nih.gov/pmc/articles/PMC2569858/

Hormonal pollution is barely on the map.
Last Edit: 10 Jan 2014 03:32 by KeithBell.

Re: Gender-bending fish downstream of WWTPs 10 Jan 2014 17:45 #6944

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The synergistic effects of exposure to natural estrogens compounded with manmade estrogenic chemicals is being observed worldwide in many species.


Occurrence of Estrogen in Wastewater Treatment Plant
and Waste Disposal Site Water Samples

nywea.org/clearwaters/08-3-fall/05-EstrogenInWastewater.pdf

Sanitation-challenged India
webcache.googleusercontent.com/search?q=...mp;ct=clnk&gl=us

Is this a sanitation issue?
www.theguardian.com/world/2013/dec/11/in...-upholds-ban-gay-sex

Re: Gender-bending fish downstream of WWTPs 12 Jan 2014 16:40 #6955

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So, if all steroid hormones are derived from cholesterol, what regulates cholesterol? Microbes.

How interesting that probiotic supplements are known to lower cholesterol:
www.ncbi.nlm.nih.gov/pubmed/23498020
newsroom.heart.org/news/daily-doses-of-a-new-probiotic-239562
well.blogs.nytimes.com/2013/02/18/really...n-lower-cholesterol/

Gender change is big business in the world of tilapia where all fish are made male:
www.thefishsite.com/fishnews/9563/drug-i...ex-change-for-profit

The alphaproteobacteria, Wolbachia, is famous for regulating gender in host offspring:
arstechnica.com/science/2011/10/meet-wol...d-chomping-bacteria/


Now let's get into the territory of the human womb, still commonly believed sterile. How might microbiota influence gender identity? The womb is not sterile and was never meant to be sterile:
www.nytimes.com/2013/08/29/science/human...ed-before-birth.html

I believe human brain development in the womb relies on omega-3 fatty acids of microbial origin, both maternal and fetal gastrointestinal tract. The fetal liver and GI tract develop long before the fetal brain.
www.plosone.org/article/info%3Adoi%2F10....journal.pone.0020146

In the third trimester, the fetal brain triples in weight while the mother's flora shifts to a diabetic state:
www.sciencedaily.com/releases/2012/08/120802122506.htm
www.cell.com/retrieve/pii/S009286741200829X

The section of the brain's hypothalamus regulating circadian rhythm and many other things including important hormones, is the suprachiasmatic nucleus (SCN), curiously doubled in size/cells in homosexual men:
www.ncbi.nlm.nih.gov/pubmed/2085769

Perhaps the only decent review of how gut microbiota regulate gut hormones while most experts still believe hormonal changes seen in diabetes have nothing to do with microbes: www.medscape.com/viewarticle/714569_4

Gender issues overlap with mental and physical health issues illustrated by commonalities in obesity with autism, homosexuality (obesity is studied in the lesbian population), anorexia . . . all matters of microbial imbalance.
articles.latimes.com/2012/apr/08/health/...ese-mothers-20120409

The key is to maintain diversity, both human and microbial, not possible in a world defecating in water.
Last Edit: 12 Jan 2014 16:45 by KeithBell.
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